BIOSC-116 Lecture Notes - Lecture 8: Thyrotropin-Releasing Hormone, Posterior Pituitary, Anterior Pituitary

• School: Diablo Valley College
• Department: Biological Science
• Course: BIOSC-116
• Professor: Khan

Document Summary

There are two hormones involved in lactation prolactin and oxytocin. Other roles inhibits menstruation in females and causes impotence in males. Role in lactation stimulates milk production. Stimulatory factors prh (prolactin releasing hormone), trh (thyrotropin releasing hormone) and oxytocin cause prolactin release. Inhibitory factor dopamine (also known as pif = prolactin inhibiting factor) decreases prolactin release. Consequences of trh"s dual roles in thyroid and prolactin regulation and the relationship to infertility excess prolactin will inhibit trh which will then cause less thyroid hormone production and hypothyroidism (high prolactin can cause hypothyroidism). Also, with hypothyroidism where there is low thyroid hormone, there won"t be feedback inhibition from thyroid hormone on trh and so there will be high trh levels, which will cause excess prolactin secretion (hypothyroidism can cause high prolactin). The resultant high prolactin will cause cessation of menses in females (and infertility) and impotence in males. Source oxytocin is released from the posterior pituitary gland.