PSYCH 14 Lecture Notes - Lecture 18: Cardiovascular Disease, Thiamine, East Los Angeles College
Document Summary
Faster/ higher intensity effect = greater addiction potential. Primarily mesolimbic dopamine pathway and endorphin/ opioid systems) More tolerance and more intense tolerance = more addiction. Individual differences in reaction to drug, metabolism of drug and severity of side effects. Affects almost every organ and system in the body. Stomach (20%) and intestines (80%) metabolized in liver (cannot be stored) Average person can metabolize 1oz of 90-proof liquor or 12 oz beer / hour, if more bac will rise. Slurred speech, lack of coordination, unsteady gait, nystagmus, (involuntary to-and-from movement of eyeballs when looking upwards or to the side), impaired attention or memory. Easy to build up tolerance and withdrawal symptoms can be severe. Dirty drug: affects almost every other system, huge number of physical effects. Problematic pattern of alcohol use leading to clinically significant impairment or distress- at least 2 of the following symptoms. Etoh used for larger amounts or over longer period than intended.
