BSC-2010 Lecture Notes - Lecture 3: Release Factor, Hydrolysis, Catabolism
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24 Apr 2017
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Importance: if we build a molecule with a radioactive element (like dna with radioactive phosphorus, or protein with radioactive sulfur) we can now see or trace where the molecule is. 1928: griffith worked with two strains of streptococcus pneumoniae one pathogenic (smooth) and one harmless (rough), the smooth bacteria produced a peptidoglycan that makes it impossible for phagocytosos to occur - thus lethal. Dr. dennis: rough bacteria could be phagocytosed - thus non-lethal, when he mixed heat-killed remains of the pathogenic strain with living cells of the harmless strain, some living cells became pathogenic. Instead, pairing a purine with a pyrimidine resulted in a uniform width consistent with the. Dna strands are elongating: helicases are enzymes that untwist the double helix at the replication forks, single-strand binding protein binds to and stabilizes single-stranded dna until it can be used as a template. Wednesdays 5:15-6:15, kin 1024: topoisomerase corrects overwinding ahead of replication forks by.
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