BIOL 102 Lecture Notes - Lecture 16: Oncogene, Cytokinesis, Allosome
Document Summary
Human cells go through mitosis because it is how we make more somatic (non reproducing cells) Before you go to g1-s, g2-m, and a midpoint of m checkpoint you have to pass the checkpoint. Making sure there"s no damage to the dna. Make sure that it was split properly. Proteins are gonna be the most important here with the ability to respond in the way it needs to. Once the cyclin degrades the phosphorylated target protein falls off. Checkpoint proteins are sensors that determine if the cell is in proper. Cell cycle will be delayed until problems fixed or prevents division entirely. Amount of cyclins varies through cell cycle. The kinases controlling cell cycle must bind to a cycle to be active. Regulation of a few proteins can control the function of a large number of cellular functions. Cancer occurs when the regulation of the cell cycle is disrupted.
