NURS 2061 Lecture Notes - Lecture 18: Central Nervous System Depression, Hypoventilation, Analgesic

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Not completely known, but is suspected to binds to opiate receptors in the cns. Alters the perception of and response to painful stimuli while producing generalized cns depression. Cns: confusion, mild sedation, dizziness, headache, euphoria. Call hcp: chest pain, weak, shallow breathing, amenorrhea, low cortisol levels (n/v w/ loss of appetite, dizziness, and worsening tiredness) Mechanism of action low intrinsic activity at receptors of the u-opioid type (morphine-like). Cns effects include depression of spontaneous respiratory activity and cough, stimulation of the emetic center, and sedation. Usually given as an injection (subcutaneous), but also nasal spray. Do not use if you have an allergic reaction to morphine. Do not take if you are taking sodium oxybate (ghb) or drink alcohol. Confusion, constipation, dry mouth, itching, seizures, sweating. Used for treating or preventing moderate to severe pain due to surgery or labor.

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