NURS 3610 Lecture Notes - Lecture 16: Hemolytic Disease Of The Newborn, Ectopic Pregnancy, Alloimmunity
Document Summary
Blood types: rh: positive or negative (rh incompatibility, abo blood groups (abo incompatibility) Iso-immunization: due to fetal- maternal blood group incompatibility, maternal antibodies fight fetal blood group antigen. Other electrolyte antigens: kell, duffy, kidd, lewis: common routes of maternal sensitization are: Associated w/ delivery, trauma, spontaneous or induced abortion, ectopic pregnancy, or invasive obstetric procedures: pathology. Maternal antibodies can cross the placenta during pregnancies in alloimmunized women and if the fetus is positive for these specific erythrocyte surface antigens, result in hemolysis of fetal erythrocytes and anemia. Causes hemolytic disease of newborn: abo incompatibility. Example: maternal blood type is o and fetal blood type is a. Maternal anti-a and anti-b antibodies may cause hemolysis of infant"s blood after birth. Newborn should be carefully assessed (look for signs of jaundice and related symptoms: rh sensitization. Can occur when rh negative woman carries rh positive fetus.
