PSY-B - Psychology PSY-B 320 Lecture Notes - Lecture 13: Homeostasis, Antipsychotic, Barbiturate

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Functional/cellular tolerance, behavioral/learned tolerance, activities of brain cells adjust to minimize effects of the substance. Tolerance: co(cid:374)(cid:272)ept of (cid:862)homeostasis(cid:863) body is trying to compensate for drug effects and maintain a state of balance. Three types of tolerance: metabolic tolerance, functional tolerance, behavioral or learned tolerance. Increase in amount of enzymes used to break down substance: people learn to cope with being intoxicated. Tolerance & sensitization relevance: for some drug therapies, continued use of the drug results in less effectiveness. Tolera(cid:374)(cid:272)e (cid:373)ay u(cid:374)derlie the de(cid:272)li(cid:374)e i(cid:374) the drug"s (cid:271)e(cid:374)efi(cid:272)ial effe(cid:272)ts: for some drug therapies, a drug must be taken for a number of weeks before it has beneficial effects. E(cid:374)sitizatio(cid:374) (cid:373)ay u(cid:374)derlie de(cid:448)elop(cid:373)e(cid:374)t of the drug"s (cid:271)e(cid:374)efi(cid:272)ial effe(cid:272)ts. Note: you can actually develop tolerance to one effect of a drug and sensitization to another. One can classify a drug by its most pronounced behavioral or psychoactive effect. Can also produce general anesthesia, coma, and death: benzodiazepines.

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