MBI 131 Lecture Notes - Lecture 9: Macrophage, Rickets, Phagocytosis
27 Sep 2016
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Document Summary
Model for disease process: agent: cause of the disease or health problem, host: susceptible person or organism, environment: factors that inhibit or promote disease. Cause injuries such as broken bones, burns, internal organ damage, concussion etc: chemical agents. Injuries or possible cellular damage leading to cancer development. Damage to lung cells: mesothelioma (rare form of lung cancer, nutrient agents. Rickets (abnormal bone development, slow growth: genetic agents. 2 recessive genes: cf disease (excess mucus disrupts function of lungs and other organs) 1 dominant hd gene is sufficient to cause disease: nerve degeneration, neurological disease, severe dementia, psychological agents. Multi-causation disease model: many chronic diseases have complex etiologies. Example heart disease, diabetes: individual genetic endowment, impact of personality, beliefs, behavioral choices, complex environment. Role of susceptible host in the disease process: susceptible host. Person who has the characteristics required to develop a given disease. Factors that influence host susceptibility to infection: non-specific innate and barrier defenses.
