BIO 350 Lecture Notes - Lecture 1: Walther Flemming, Thomas Hunt Morgan, Friedrich Miescher
Document Summary
All living organisms contain dna, rna, and protein: few exceptions (rna viruses) sequence information is transferred dna > rna > protein, central dogma. 1859: charles darwin published theory of evolution by natural selection, he believed we inherited every trait and it has a function, any variation which is not inherited is unimportant for us. 1866: gregor mendel discovers basic rules of inheritance, father of genetics. 1871: friedrich miescher discovers nuclein (wbc interest, nuclein obtained from cells extracted from bandages of soldiers wounded in. Crimean war: most whole blood samples don"t have nuclein, wbc (white blood cells) have a ton. Molecular biology is essentially the marriage of biochemistry and genetics. 1879: walther flemming discovers chromosomes, produced a catalogue of aniline dyes, a by-product of coal tar, to stain cells of salamander embryos. 1902: walter sutton links chromosomes to inheritance, worked with grasshoppers. 1916: thomas hunt morgan laboratory established that genes reside on chromosomes.
