BIOL 2299 Lecture Notes - Lecture 5: Spindle Apparatus, Sister Chromatids, Nuclear Membrane

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Somatic cells(cells of the body) contain fixed number of chromosomes(humans have 46 chromosomes) Chromosomes come in pairs(23 pairs in humans) Somatic cells are diploid-they contain two copies(one from mom and one from dad). Germ cells(or gametes) are haploid and contain one set of chromosomes-one of each pair. Haploid gametes unite in fertilization to produce diploid somatic cell(diploid has one type of each from each parent) Mitosis: process of chromosomal segregation and cell division that results in two genetically identical daughter cells. Each chromosome consists of two sister chromatids(duplicated chromosome in. Mitotic spindle forms and attaches to centromere a region called the kinetochore. Chromosomes move toward the center of the cell until all the kinetochores lie on an imaginary plane equidistant from the spindle poles=the metaphase plate. Centromeres divide longitudinally, and the two sister chromatids of each chromosome move toward opposite poles of the spindle.

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