BIOL-UA 21 Lecture Notes - Lecture 4: Eukaryotic Initiation Factor, Telomerase Rna Component, Peptide Bond
15 May 2016
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Document Summary
Lecture 9/16: central dogma iii-protein synthesis and properties. C terminal domain on rna polymerase: scaffold on which all reactions (cleavage, polyadenylation, etc. ) occur. The core of telomerase rna adds sequences to chromosome ends which would otherwise become shorter every cell divisions. The genetic code: codes used to translate from nucleic acids to amino acids. Contains some unusal nucleotides: dihydrorouridine, insoine, ribothymidine, pseudouridine, methyl groups. Anticodon: three bases that base pair to the codon. Acceptor stem: gets attached to correct amino acid. A, c, u, g, i can be in anticodon. C base pairs with g, a base pairs with u. In third position of codon, first position of anticodon: g can base pair with c or u, u can base pair with a or g, i can base pair with c/a/u. Tetrahedral alpha-carbon connected to amino group, carboxyl group, r side chain.
