HED 044 Lecture Notes - Lecture 9: Randomized Controlled Trial, Statistical Hypothesis Testing
2 Nov 2020
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The role of epidemiology in public health (part 2) Relate group-level statistics on e and d. Measure e and d at the same time. Select people +/- disease and measure prior e. Measure e and follow healthy people for new d. Assigned healthy people to +/- e and follow for d. Compare disease frequencies in populations based on a factor of interest. Cofounder: a third factor related to both exposure and disease which distorts the true relationship between exposure and disease. Cases: need to be incident, fit a standard case definition. Controls: free of disease and from the same population that produced the cases. Descriptive study designs > limited, hypothesis generation. Allows for estimation of disease risk in a population. Analytic study designs > better, hypothesis testing. Allows for estimation of the disease risk associated with some exposure. Which study design you choose depends on many factors.
