NROSCI 0081 Lecture Notes - Lecture 5: Anandamide, Synaptic Plasticity, Reuptake
Document Summary
Process by which a neuronal signal is transferred through a neuron, and from one neuron to the next: signaling molecules are released by presynaptic neuron and activate receptors of postsynaptic neuron. Neurotransmitter: chemical messengers that carry the message of the nerve impulse across the synapse: criteria. Chemical must be produced or found within a neuron. Chemical must be released in response to an action potential. When released, chemical must act on a receptor and cause a biological effect. If applied exogenously experimentally, it should have the same effect as when released by a neuron: classes. Neurotransmitter receptors: ionotropic receptors embedded membrane protein with two parts. A binding site for neurotransmitter in order for nt to elicit effect on outside of the membrane. A pore that regulates ion flow to directly and rapidly change membrane voltage: metabotropic receptor. Do(cid:374)"t let a(cid:374)ythi(cid:374)g th(cid:396)ough embedded membrane protein with binding site for nt but no pore. Alters ion flow in a membrane channel.
