01:119:115 Lecture Notes - Lecture 8: Citric Acid Cycle, Acetyl-Coa, Oxidative Phosphorylation

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Introduction to cell respiration: overview of eukaryotic respiration. C6h12o6 +6o2 6o2 + 6h2o + e (as atp) Stored e that will be used to make atp. 4 stages: glycolysis, oxidation of pyruvate acetyl co, the citric acid cycle, oxidative phosphorylation. Account for the electrons and each stage. Tear apart sugar and transfer energy to nadh and fadh2. Make atp: glycolysis (9 enzymes that help) (breaking down of glucose) Function: convert 1 glucose 2 pyruvates, 2 net atp. Glucose enters cell (mammals) via facilitated diffusion by glut1. 1 glucose converted to 2 g3p (glyceraldehyde 3-phosphate. 2 g3p converted to 2 pyruvate, 2 nadh, and 4 atp (profit from inv) *phosphate groups removed transferred to adp to form new atp. Build 2 atp: oxidation of pyruvate to acetyl coa (2 co2, -2 + 4 atp, 2 +2 nadh, 0 fadh2. Why: converts pyruvate to acetyl coa, outer mitochondrial membrane- diffusion through small pores, inner mitochondrial membrane: carrier protein.

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