01:119:115 Lecture Notes - Lecture 20: G. H. Hardy, Wilhelm Weinberg, Allele Frequency

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Evolution= change in populations over generations not changes in individuals over their lifetime individuals do not evolve. Natural selection acts on individuals but only populations evolve. Microevolution= minor evolutionary changes of populations over a few generations = change in allele frequencies in population over generations. Genetic variations are necessary for evolution to occur: variation among individuals, phenotypic variations. Phenotype= product of inherited genotype + environmental influences. 2 types of phenotypic variations genetically determined environmentally determines only genetically determined part of phenotype variation can affect evolution natural selection can only act on variation with a genetic component: sources of genetic variation. Three mechanisms cause allele frequency change: natural selection, genetic drift, gene flow. Genetic variation among individuals in genes ot nucleotide sequences. Can be measured as gene variability or as nucleotide variability. Focus on gene variability: formation of new alleles, alterations in chromosome structure, rapid reproduction, sexual reproduction, formation of new alleles. Mutation random change in nucleotide of dna.

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