01:119:116 Lecture Notes - Lecture 21: Gastrointestinal Tract, Gallbladder, Gastric Glands

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Trace a meal through digestive tract, include all enzymes and organs. Extracellular digestion- breakdown in compartments that are continuous with the outside of body, can eat big things. Entire meal- starting at mouth to all structs. Gets bolus into stomach and moves food throughout. Stomach lining- many pits to tubular gastric glands. Parietal cells- atp driven pump to put h+ into lumen help lower ph in stomach. Removes short segment of polypeptide chain from pepsinogen exposes active site of enzyme exposes active site of enzyme. Makes chyme ph 2, small polypeptides, mucus, smaller carbs. Bile- produced in liver, stored = gall bladder. Bile salts- help to digest fats- no enzymes. And two that remove 1 aa at a time. Bile salts- stick (adhere) to fats and emulsify them pancreatic lipases-> glycerol, fatty acids, monoglycerides. Glycerol and s single fatty acid- simple diffusion across intestinal epithelium.

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