01:146:328 Lecture Notes - Lecture 3: Amphotericin B, Rosiglitazone, Leishmania Major

• School: Rutgers University
• Department: Cell Biology and Neuroscience
• Course: 01:146:328
• Professor: Professor Fong

Document Summary

Lower level of binding protein maybe part of hdl: not sure if its hdl, but he means the ability for the immune system to detect and atack parasites by recognizing speciic proteins. Trypanosome- changes coats ever 100 replicaions: the concept is vsg, 100 large chromosomes, expression link body, in mini chromosomes, drugs used is heavy arsenic along with one other drugs. Trypanosome- iniially afect cats as it spreads through kissing bugs: both male and female and larva can bite, not all trypanosome only afect cats, they poop when they eat, we scratch, it enters our blood stream. Read cdc website to learn the life cycle. 1966- hofman roche- benzznidazole: 1970- bayer created nifurimaox- to ight human african trypanosomiasis. Chagas disease- south america- highest infecion rate for trypanosomiasis. How do you get trypanosomiasis (america: romana syndrome, scratch the poop into blood, read botom science for bruzei and one other thing, intake of contaminated food.