01:146:328 Lecture Notes - Lecture 21: Strongyloides Stercoralis, Ivermectin, Parthenogenesis
20 May 2016
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Document Summary
Acaris lumbricoides (a. suum) part of the unholy trinity: history: Most common/abundant parasitic infection in the world. Unique resistance to chlorination and other chemicals and environmental changes like drop/rise in ph and/or temperature. Adult worms live in the lumen of the small intestine. A female may produce approximately 200,000 eggs per day, which are passed with the feces. Unfertilized eggs may be ingested but are not infective. Fertile eggs embryonate and become infective after 18 days to several weeks, depending on the environmental conditions (optimum: moist, warm, shaded soil). After infective eggs are swallowed, the larvae hatch, invade the intestinal mucosa, and are carried via the portal, then systemic circulation to the lungs. The larvae mature further in the lungs (10 to 14 days), penetrate the alveolar walls, ascend the bronchial tree to the throat, and are swallowed. Upon reaching the small intestine, they develop into adult worms: pathology: Infection can be accomplished through ingestion of fertilized eggs.
