01:146:328 Lecture Notes - Lecture 6: Kinetoplast, Flagellum, Haptoglobin
20 May 2016
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1, 2, 3, 6) and chan et al 2012 paper. Hat: west african hat gambian and east african hat rhodisian: history. Waf: t. brucei = gambiense (glossina palpalis) - 90-95% Flies pass along the trypanosomes (vectors kissing, conenosa, assasin bugs . Panstrongylus megutus: life cycle: http://www. edcgov/dpdx/az. html, diagnosis: look for worm like molecules in blood molecules, pathology: Variant surface glycoprotein (vsg): can change its surface protein and evade immune response. Gene conversion: moving the gene of expression site body (esb) Multicellularity (coanoflagelate gk substrate social : a condition or state of having or being composed of many cells or more than one cell performing differing functions, gk enzyme with atp + gtp substrate, paraflagellar rod. Rna interference demonstrated function from genome data: sleeping sickness morphological shape examples: Amiasis: smaller shape, basal body behind the nucleus ( no flagella ) Promiasis: medium sized shape, basal body all the way to the far behind. Phytomonas: lives without heme: heteroxenous and monoxenous.
