01:146:356 Lecture Notes - Lecture 21: Kallikrein, Kidney Stone Disease, Afferent Arterioles

• School: Rutgers University
• Department: Cell Biology and Neuroscience
• Course: 01:146:356
• Professor: Gary Merrill

Document Summary

Systems physiology lecture 11 notes: renal/urinary system (day 2) Bo(cid:449)(cid:373)a(cid:374)"s pa(cid:272)e: (cid:449)here the (cid:448)as(cid:272)ular a(cid:374)d epithelial (cid:373)eet, the poi(cid:374)t (cid:449)here the filtrate passes through from the vascular system into the tubular system. E(cid:374)d of the as(cid:272)e(cid:374)di(cid:374)g li(cid:373)(cid:271) of he(cid:374)le"s loop, leads to the tu(cid:271)ules. (cid:862)gra(cid:374)ular (cid:272)ells(cid:863) (cid:272)o(cid:374)tai(cid:374) e(cid:374)zy(cid:373)es that (cid:272)a(cid:374) adjust syste(cid:373)i(cid:272) arterial (cid:271)lood pressure. Filter of four layers from inner most to outermost. Glycoclex: glypo proteins that carry a charge; part of the bbb (blood brain barrier) Fenestration: endothelial cells present so that larger molecules can pass through. Fenestrations are large holes that provide no restriction to the movement of water, and other molecules out of the lumen of the capillary. Basement membrane: wraps around these inner layers. Podocytes: wrap around all of the others. 2) destretch of afferent arteriole and renin release. Tubular epithelial cells: amplified surface area, finger like.