01:146:356 Lecture Notes - Lecture 26: Ascending Limb Of Loop Of Henle, Cytosol, Membrane Potential

• School: Rutgers University
• Department: Cell Biology and Neuroscience
• Course: 01:146:356
• Professor: Gary Merrill

Document Summary

System physiology notes: renal system- sodium exchange and water (day 1) Figure 35. 5: absorption of na+ salt in different segments of a nephron. Proximal and thick ascending limb are more complex!!! Basal: the flat, horizontal line in each top and bottom of the blob. Lateral: the vertical line with lots of interactions taking place. 1) sodium from tubular lumen moves to cytosol. 2) sodium moves from cytosol to interstitial space. 1) na moves into first step over an electrochemical gradient. 2 ++ inside and 3+++ outside of cell = + 1 net loss. 1+ in 1+ out = no net charge created, no potential created. Thick ascending wall also completes a sodium process but uses the co transport and does not create a net charge. 2 cl- for 1na+ and 1 k+ Most of the water in the body is inside cells. Most water, sodium, and ultra filtrate reabsorb in proximal tubules.