01:694:301 Lecture Notes - Lecture 20: Light-Independent Reactions, Transketolase, Ribulose

• School: Rutgers University
• Department: Molecular Biology and Biochemistry
• Course: 01:694:301
• Professor: F Deis

Document Summary

Nadh is oxidized by respiratory chain to generate atp. Ribose 5-phosphate can be converted g3p and f,6-p by these enzymes: these enzymes create a reversible link b/w ppp and glycolysis by catalyzing 3 successive rxns: The net result of these rxns is the formation of 2 hexoses and. 1 triose from 3 pentoses (1) formation of ga3p/sedoheptulose 7-phosphate from 2 pentose (5) Pp can interact to provide the products which are needed by a cell (modes fig. 20. 23: mode 1 much more ribose 5-phosphate than nadph is required. Utilize the non-oxidative branch to make r5p. Mode 2 the needs for nadph and for ribose 5-phosphate are balanced. Utilize the oxidative branch to make both nadph and r5p: mode 3 much more nadph than ribose 5-phosphate is required. First run oxidative branch to form 2 nadph and ribose 5-p. Then ribose 5-p f6p and g3p (transketolase, transaldolase) G6p resynthesized by from f6p and g3p by gluconeogenic pathway.