BIO 212 Lecture Notes - Summer 2018 Lecture 8 - Ascending limb of loop of Henle, Collecting duct system, Aldosterone

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Renal physiology summery: total body water is distributed between. As percentages of body weight, 60% is total body water, 40% is. These shifts produce changes in ecf and icf volume: renal clearance is the volume of plasma cleared of a substance per unit time and is determined by its renal handling. Substances with the highest clearances are both filtered and secreted. If any of the starling pressures change, net ultrafiltration pressure and. Gfr are altered: reabsorption and secretion modify the ultrafiltrate that is produced by glomerular filtration. The net reabsorption or secretion rate of a substance is the difference between its filtered load and its excretion rate. Glucose is reabsorbed by a tm-limited process: when the filtered load of glucose exceeds the tm, then glucose is excreted in the urine (glucosuria). In the distal tubule and collecting ducts, 8% of the filtered. K+ across cell membranes and by renal regulation.

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