BIOL 304 Lecture Notes - Lecture 5: Rh Blood Group System, Sickle-Cell Disease, Zygosity
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Incomplete dominance & codominance: some alleles are neither dominant or recessive, many traits are controlled by multiple alleles or multiple genes. Incomplete dominance when one allele is not completely dominant over another: both alleles are partially dominant. If the genotype is heterozygous, the phenotypes become a blend : ex: red + white = pink, examples of genotype possibilities rr (red), ww (white), and it produces rw (pink) Co-dominance: co-dominance when both alleles are equally dominant and are expressed at the same time. Inheritance of blood type: co-dominance occurs when both alleles are fully dominant, the result of this is both alleles being expressed and two distinct phenotypes being observed. Human blood types: a, b, ab, o. Ib type b i type o (recessive) Possible genotypes: type a ia ia(homozygous), ia i (heterozygous, type b ib ib (homozygous), ib i (heterozygous, type ab ia ib (codominance, type o ii.
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These all relate to exceptions to the inheritance patterns encountered by Mendel.â
Why do multiple and lethal alleles often result in modifications of the classic Mendelian monohybrid and dihybrid ratios?
Select the four correct statements.
-When an essential gene is mutated, it can result in a lethal phenotype. There are no classic Mendelian monohybrid and dihybrid ratios. |
-In the case of codominance, heterozygotes produce gene products from both alleles of a gene. Classic Mendelian monohybrid and dihybrid ratios are modified by codominance. |
-In the case of incomplete dominance, the phenotype of the heterozygote is distinct from and often intermediate to the phenotypes of homozygous individuals. Classic Mendelian monohybrid and dihybrid ratios are modified by incomplete dominance. |
-Genes exist in a large number of allelic versions and a diploid organism has two homologous gene loci that may be occupied by different alleles of the same gene. This can result in many different phenotypes for traits, which may not follow typical Mendelian ratios. |
-When an essential gene is mutated, it can result in a lethal phenotype. This results in a modification of classic Mendelian ratios. |
-The phenotype of the heterozygous genotype is distinct from and often intermediate to the phenotypes of the homozygous genotypes. The joint expression of both alleles in a heterozygote is called codominance. There are no classic Mendelian monohybrid and dihybrid ratios. |
-Genes exist in a large number of allelic versions, but in a diploid organism, only one allele of the gene can occupy one homologous gene loci. Classic Mendelian inheritance cannot explain this phenomenon. |
-Each gene produces a unique gene product. The effect of one allele in a heterozygote completely masks the effect of the other. Classic Mendelian genetics cannot explain this phenomenon. |