PHS 2101 Lecture Notes - Lecture 12: Roll Back Malaria Partnership, Wellcome Trust, Sub-Saharan Africa
14 May 2019
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Document Summary
Malaria statistics: 219 million cases and 435,000 deaths in 2017, 21% decline in incidence 2010-2015, malaria mortality rates declined 29, 70% malarial deaths are in children under 5 yrs, 2015-2017 progress has stalled. Plasmodium falciparum: multiple stages of parasite development (life cycle) very complicated, complex life cycle: gut of mosquito; human liver and blood stream, monkeys - parasite reservoirs, transmitted to humans through mosquito bites. Clinical picture: febrile illness (causes high fevers, severe anemia (peaks of fever, cerebral malaria, serious complications in pregnancy, relapsing fevers (they"re fine and then they"re not, risk of transmission, eir in africa = 1,000 bites per person/year. Global efforts toward malaria control: multilateral initiative on malaria, nih, wellcome trust, gates foundation, roll back malaria (who) Methods for malaria control: vector control, can drain swamps, reduce mosquito population possibly reduce malaria transmission. Improving access to treatment: need new treatment strategies. In infancy and childhood: during pregnancy b, combination therapies, artemisinin.
