PSY 250 Lecture 3: Lecture #3

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When referring to concentration it refers to the ions inside and outside of the cell. When there is an uneven distribution of inside and outside ions within the cell it causes a current flow. The difference is the electrical charge is more between -60 to -80 mv: what factors underlie the uneven ionic distribution across the cell membrane? (i) selective permeability of the membrane controls passive diffusion of molecules. Called semi permeability because it is controlled it is gated by either voltage or ligand, the membrane itself is fat soluble. Sodium ions want to move in because it is positive and because it is pulled by both the concentration high outside and low inside, positive outside and negative inside. That"s how current flows: from positive to negative. Chloride will want to come in but it cannot because it is negative charge. Despite not being fat soluble, able to move in through ion gate (ii) na-k pump.

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