BIO 326 Lecture Notes - Lecture 11: Nucleolus, Nuclear Lamina, Chromosome Territories
Document Summary
Lecture 11: molecular structure and organization of chromosomes (chapter 12) Provide information needed for gene expression (dna is the template in transcription; ch. Store and pass on genetic material (cell division; ch )-> creates patterns of inheritance (ch 4,5,7,8) The dna molecule functions through its nucleotide sequence. Gene expression-> specify the nucleotide sequence of rna and consequently, amino acid sequence of proteins. Proper segregation of chromosomes in cell division (centromere, not the right sequence, the kinetochore cannot associate properly and cannot move the chromosomes to one side of the cell. ) Compaction of chromosomes (so if they can fit in the cell) Dna is a double helix, but the nucleotide sequence creates its exact shape. Proteins bind to dna by fitting together with its exact shape. Proteins must bind to dna in order to . Carry out transcription and dna replication (rna polymerase, dna polymerase respectively) Segregate and compact chromosomes during cell division.