BIO 185 Lecture Notes - Lecture 5: Mutation Rate, Secondary Sex Characteristic, Genetic Variation

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Genetic variation: gene variability can be quantified as the average percentage of loci that are heterozygous (2 diff alleles for a given locus, nucleotide variability (variation at the molecular level of dna, without genetic variation, evolution cannot occur. Sources of genetic variation: originates when mutation, gene duplication, or other processes produce new alleles and new genes, new alleles can arise by mutation, a change in the nucleotide sequence of an organisms dna. The result is an expanded genome with new genes that may take on new functions: such increase in gene number appear to have played a major role in evolution. For example, the remote ancestors of mammals had a single gene for detecting odors that has since been duplicated many times. As a result, humans today have about 350 functional olfactory receptor genes, and mice have 1000. Rapid reproduction: mutation rates are even lower in prokaryotes.

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