CJ 4002 Lecture Notes - Lecture 6: Opioid Receptor, Opioid, Hydromorphone

• School: Temple University
• Department: Criminal Justice
• Course: CJ 4002
• Professor: Steven Belenko

Document Summary

Derived from morphine, extracted from the seed pod of the opium poppy. Used as analgesic in ancient egypt and greece. Laudanum (alcohol and opium) used for pain relief and to aid sleep from 1500s to late 19th c. Morphine and opium widely used in 19th c. Legal under federal law until early 1910s. Mimic natural endorphins in the brain at opioid receptor sites. Can be injected, smoked, snorted, or taken by pill (synthetic opioids) A commonly abused drug: 33. 1 million aged 12+ have ever used an opiate for nonmusical purposes (13. 3%) High likelihood of physical dependence when used non-medically. Sold on streets in diluted powder form. Street drug purity has increased from 4% in early 1980s to 25% in 200s, now range of. Increasing use in past decade (especially 18-15 y/o) Initial rush within 7-8 seconds of intravenous injection, 10-15 minutes if smoked or snorted. Euphoria, skin ush, drowsiness, impaired mental function. Risk of overdose where purity is unknown.