BIO-0014 Lecture Notes - Lecture 29: Vascular Resistance, Ejection Fraction, Stroke Volume

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Walls absorb some energy from increased volume- systolic pressure not too high. Energy returned to blood- diastolic pressure not too low. If large arteries were unable to stretch during systole then: All energy would be pounding against walls, not being absorbed. Most smooth muscle for size- radius of arterioles can change dramatically- If blood pressure too low- body tissues won t receive enough blood to carry out metabolic functions. If blood pressure too high- body tissues can be damaged by the increased force. Q= cardiac output = heart rate * stroke volume. Delta p= mean arterial pressure- central venous pressure. Central venous pressure (right atrial pressure) is around 0. Mean arterial pressure = cardiac output * total peripheral resistance. Map = heart rate * stroke volume * total peripheral resistance. Bp increases- carotid sinus stretches- afferent neurons excited- generate more action potentials. Bp decreases- carotid sinus less stretched- afferent neurons less excited- decreased action potentials.

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