BSC 108 Lecture Notes - Lecture 5: Tumor Suppressor Gene, Human Papillomavirus Infection, Sickle-Cell Disease

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Cell cycle regulation p53 normally helps suppress the formation of tumors; tumor suppressor gene. Normal growth in plants and animals requires careful regulation. Skin cells divide frequently throughout life, but liver cells divide only when needed (perhaps to heal a wound) Some specialized cells do not divide at all, such as nerve cells. Normal plant and animal cells have a cell cycle control system. Proteins that integrate information and send stop or go ahead signals at key points in the cell cycle. Both plant and animal cells can become cancerous which means they are growing out of control. What is cancer: a disease that claims the lives of 1 out of every 5 people in the us, a disease of the cell cycle. Cancer cells do not respond normally to the cell cycle control system. It can spread to other parts of the body. A person with malignant cancer cells is said to have cancer.

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