BSC 300 Lecture 10: 2-13-18
Document Summary
Important concepts to remember: the citric acid cycle and fatty acid oxidation: Summary of aerobic oxidation of glucose and fatty acids: cytosol: glycolysis. Pyruvate and fatty acyl coa-- diffuse through porins into the mitochondrion. Inner membrane transport proteins-- transport pyruvate and fatty acids into the matrix. Cytosolic nadh electrons shuttled to nad+ in the matrix: mitochondrial matrix: pyruvate dehydrogenation, citric acid cycle and fatty acid oxidation. Pyruvate-- converted to acetyl coa with the formation of nadh and co2 (diffuses out of the mitochondrion and cell) Fatty acyl coa-- two carbons converted to acetyl coa with formation of fadh2 and. Acetyl coa oxidation in the citric acid cycle generates nadh and fadh2, gtp, and co2. Inner membrane: electron transport and proton motive force. Nadh and fadh2 transfer energetic electrons down the electron transport chain. Electrons transferred through electron-transport complexes to o2 (diffuses into cell and mitochodrion matrix)