BSC 431 Lecture Notes - Lecture 33: Skeletal Muscle, Stillbirth, Leishmania

• School: University of Alabama
• Department: Biological Sciences
• Course: BSC 431
• Professor: Julie Olson

Document Summary

An infectious disease caused by intracellular protozoans (apicomplexa) Require 2 hosts: mosquito (sexual reproduction) and human (asexual reproduction) (cid:1) (cid:1) (cid:1) (cid:1) After a 7-17 day incubation period, vague influenza-like symptoms (malaise, muscle pain, nausea, headache, vomiting) (cid:1) As infection progresses, chills, fever, and malarial rigors (about every. The 5 species share a common life cycle. Introduces infectious plasmodia sporozoites via saliva into the circulatory system (cid:1) Sporozoites are carried to the parenchymal cells of the liver, where asexual reproduction occurs (cid:1) (cid:1) Can establish dormant phase w/ no cell division: activation months to years later (relapsing malaria, p. vivax, p. ovale. Hepatocytes rupture, releasing the merozites which attach to specific receptors on the surface of erythrocytes, initiating the erythrocytic cycle (cid:1) Asexual reproduction progresses through several stages in the erythrocyte. Rbc"s rupture, releasing up to 24 merozites/cell which infect new erythrocytes (cid:1) (cid:1) (cid:1) (cid:1) Some merozoites develop into male and female gametocytes.