BSCI 105 Lecture 20: DNA Things AND Lecture 21: DNA Replication

• School: University of Maryland
• Department: Biological Sciences Program
• Course: BSCI 105
• Professor: Norma Allewell

Document Summary

Griffith"s experiment: injected mice with combinations of live and dead viruses, showed that non-lethal viruses could mix with dead lethal viruses to transform into a lethal virus. Avery"s experiment: what is transformed, used dnaase, rnaase, and proteinase, found that rnaase and proteinase transformed cells. Hershey and chase: where is dna stored, labeled protein and dna, found that dna was transferred. Chargaff"s rules: base composition of dna varies among species. Bacterium: 24. 7: %a = %t, %g = %c. Using x-ray crystallography to determine molecular structure: wavelength of x-rays are about the distance between atoms of molecules. Dna: bases are held together with hydrogen bonds, g-c bonds are stronger than a-t bonds. Dna replication: dna replication is semi-conservative. Each new strand of dna is made up of one old and one new strand of. Dna: begins at origins of replication, enzyme that starts replication is dna polymerase iii. Also edits wrong dna: both strands are synthesized from 5" to 3".