KNES 464 Lecture 1: Lecture 1

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3 phosphates- high energy bond, when that bond is broken, we release energy, which is the energy our cells use to do work. At onset of exercise which of the thre systems provides greatest rate of atp resynthesis: pcr, get energy from everything at the onset, but pcr is just the highest, get the pics from slides. Dominates atp resynthesis: time: 1-10 seconds, distance: 100 eters. Creatine phosphate reaction energy released to then rephosphorylate. What happens to pcr and pi levels during exercise: pcr, decrease because we took the phosphate for atp, pi. Increases because breaking the phosphate off the atp: creatine. Atp, increae in phosphate, atp does(cid:374)"t (cid:272)ha(cid:374)ge good at buffering the concentration of atp in skeletal muscle. Cut off (cid:271)lood flo(cid:449) a(cid:374)d do(cid:374)"t get phosphocreatine back proving that mitochondria and oxygen are needed to rephosphorylate: red line exercise down, red line up exercise recovery.

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