BMB 401 Lecture Notes - Lecture 18: Glycogen Synthase, Adenosine Triphosphate, Phosphoglucomutase

• School: University of Miami
• Department: Biochemistry and Molecular Biology
• Course: BMB 401
• Professor: Harris Thomas

Document Summary

1,4" glucose chain and -1,6" branching and its plant: phosphoglucomutase catalyzes convertion of glucose 6- phosphate into a glucose 1-phosphate. Glucose 6-phosphate becomes glucose 1-phosphate and this is. 1. reversible back and forth and no regulation. 2. and this catalysis releases ppi and pyrophosphatase with the addition of water forms 2pi. 4. called glycogenin that is where this will originates. Glycogenin is the autocatalytic enzyme adds glucose onto itself. 5. and that gets recognized by the glycogen synthase enzyme which adds glucose one after the other all the way down. The branching enzyme is called the 4:6 transferase and it makes. 7. the alpha(1 6) which is the branch and there are further elongation at the nonreducing ends by glycogen synthase, making alpha(1 4) bonds and further branching making alpha(1 6) bonds to make glycogen. We have branching so we can have many terminal ends that can be released.