MIC 301 Lecture Notes - Lecture 17: Coxsackievirus, Picornavirus, Messenger Rna

• School: University of Miami
• Department: Microbiology and Immunology
• Course: MIC 301
• Professor: Williams Roger

Document Summary

2: shows the categories of rna viruses (ss and ds non enveloped and then ss enveloped, most are ss. 2 families: picornaviridae (smallest but big family, caliciviridae. Picornaviruses: naked and small, icosahedral capsid symmetry, positive rna genome (same polarity of messenger rna = can directly infect cells and start translating messenger rna in target cell) Negative rna have to make copy first and encode and carry it (the polymerase: 3 groups. Transmitted fecal/oral route so for instance contaminated water eaten by shellfish and then you eat them: slide 8 shows all diseases picornavirus causes. Hav goes to liver: most people with polio didn"t know they were infected. 2 vaccines came out and we see lots of cases before the first one and then immediately cases went down and then they introduced live vaccine and now it is all gone: rhinoviruses. Not invasive and in the nose so vaccines not great against them because they stay in one area.