MIC 323 Lecture 3: Test 1

• School: University of Miami
• Department: Microbiology and Immunology
• Course: MIC 323
• Professor: Schesser Kurt

Document Summary

Have cross linkages but instead of direct cross linkage, linked via this innerbridge: gram + thick peptidoglycan is outer layer and can have proteins in this outer surface. In gram we have thin inner membrane and then thin peptidoglycan and then periplasm in between: used as a factory to build complex stuff like attachment factors such as pili and vibriae. This is done in gram don"t forget. 11 problems of getting stuff through membrane to get out of cell: chemistry of it = protein transporters. Lecture 3: size of stuff = transport proteins unfolded, selectivity of stuff going through = signal sequences. Membrane bound sensor kinase which when bound by a ligand and then phosphorylate response regulator (add phosphate group and turns protein into active transcription factor) Results in particular genes being expressed (target genes) All this was microbe part of this, now will talk about host side of things.