BIOL 2213 Lecture Notes - Lecture 7: Facilitated Diffusion, Tight Junction, Active Transport

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1)ligand ligand binds to protein, changes protein shape & opens the channel (not. 2)voltage gated ion channel state of the channel (open or closed) depends on the membrane potential (normally negative inside, positive outside) calcium is very important in this channel. 3)mechanically gated channels: some physical disturbance (ex: bending) causes ion channel to open; ex: touch receptors in your skin. Ex: nutrient molecules from food in small intestine and get in circulatory system. Ex: material from urine being formed from kidneys move from the urine back into the blood or vice versa. For something to move through the cell, it must first cross the apical side (inside of the organ) X is moved from low concentration to high concentration in the blood; moving through cotransport from the lumen into the cell driven by the sodium gradient. X moves by facilitated diffusion from the cytoplasm inside the cell to the blood.

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