BIOL 2081C Lecture Notes - Lecture 11: Melanocortin 1 Receptor, Oca2, Epistasis
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Genes on the x-chromosome also follow a characteristic pattern of inheritance. Since males only have one x-chromosome, they only have one allele for any gene on the x-chromosome. Thus, males exhibit any phenotype associated with a mutation in a gene on their x-chromosome. Reading assignment: hartl, sections 4. 1, 4. 3 & 4. 4. If you need a refresher on meiosis, watch: meiosis (11:45 min) Learning objectives: explain mendel"s rules of inheritance (laws of segregation and independent assortment) in terms of meiosis. This individual would not be at risk for passing the disorder on to his/her offspring. X-linked (recessive): affected individuals are exclusively or almost exclusively male, affected males who reproduce have normal sons, a woman whose father was affected has normal sons and affected son in the ratio of 1:1. Normal mother (xx) x affected father (x*y: phenotype: all normal daughters: all normal sons, genotype: all normal.
