BIOL 2081C Lecture Notes - Lecture 20: Tryptophan, Lysine, Transfer Rna
Document Summary
Now that the cell has transcribed the protein into an mrna with a 5" cap, polya tail, and appropriately spliced out introns, it is moved into the cytoplasm for translation. Required video assignment: a video containing more detailed information on translation. Explain how peptide bonds are formed during translation: peptide bonds form by the complimentary base pairing of trna"s anticodon with mrna"s codon. The mrna strand is fed through the bottom of the ribosome and each section of trna enters chambers in the ribosome known as the a site and p site. From this point, once the 2 codons are matched, peptides are resulted and attach forming a chain of peptides: an rrna is the enzyme in this case. Bonds are formed by the peptidyl transferase activity found in the 28s subunit of the ribosome. In contrast, dna polymerase is a large protein-based enzyme.
