BCS 110 Lecture Notes - Lecture 21: Axon Terminal, Signify, Dopaminergic Pathways
20 Apr 2018
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Influenced by: memory, past events, consequences, future outlook. Emotional state: evidence suggests that motivated behavior involves coordinated communication between the prefrontal cortex, hypothalamus, and ( wanting ) reward circuitry, reward, reward is the positive/pleasurable consequence of an action, and it is a potent motivator. In particular, many species will administer brief bursts of weak electrical stimulation to specific sites in their own brains. This phenomenon is known as intracranial self-stimulation (icss), and the brain sites capable of mediating the phenomenon are called pleasure centers. Anticipatory pleasure: mesotelencephalic dopamine system, the mesotelencephalic dopamine system plays an important role in intracranial self-stimulation. Neurons project from the mesencephalon (midbrain) to the telencephalon: the neurons in this system have the their cell bodies in two midbrain areas: Ventral tegmentum (red: nigrostriatal pathway: substantia nigra neurons project to the dorsal striatum (degenerate in. Parkinson"s disease: mesocorticolimbic pathway: ventral tegmental area neurons project to cortical and limbic sites, including the nucleus accumbens.
