MICROM 445 Lecture Notes - Lecture 1: Intracellular Parasite, Rna Splicing, Influenza Vaccine

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5 Apr 2020
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Polymerase, in the case of negative stranded rna viruses, or other associated proteins; these are attached to the viral genome: general virus morphology essential for virus to infect the next cell. Remember: matrix proteins help connect the capsid to the envelope and help with envelope structure. Icosahedral nucleocapsids: the most efficient way to get a symmetrical shell with maximum internal volume from non-symmetrical protein building blocks. Notice the yellow spots on the virus; these are the vertices. Note that most of these dna viruses are icosahedral and double stranded: plus sense rna viruses, remember, these are the ones that can act directly as mrna. Note that all of these are icosahedral with exception of corona- viridae which has helical capsids. Also note the corona shape of coronavirus, due to the spiked proteins that externally surround the envelope: minus sense rna viruses. Very important to remember that any minus sense (negative stranded) are helical and enveloped!!!

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