BIS 101 Lecture Notes - Lecture 16: Zygosity, Gamete, Mutation

DNA damage brought on by a variety of natural and artificial agents elicits a wide variety of cellular responses. In addition to the activation of DNA repair mechanisms, there can be activation of pathways leading to apoptosis (programmed cell death) and cell-cycle arrest.

Part A

Why would apoptosis and cell-cycle arrest often be part of a cellular response to DNA damage?

(2) The process of error correction of mismatched bases from the end of a growing polynucleotide that is carried out by DNA polymerases is called ________.