PSC 130 Lecture Notes - Lecture 17: Dentate Gyrus, Electroconvulsive Therapy, Entorhinal Cortex
Document Summary
March 14, 2017: neurogenesis, neurogenesis, new neurons are generated in the adult brain in the hippocampus (i. e. dentate gyrus, before, it was believed that neurons were only reproduced in early childhood up to age. *dg supports sparse and orthogonal representations (episodes? primarily involved during encoding. Dg, there is very little activation/ very little firing: dg is storing orthogonal representations very distinctive for specific events, dg important for encoding that transfers info to ca3 and. 2-3 weeks are mature cells, and connect dg with ca3. Particularly sensitive to new learning: nature of the cells (based on rat studies) [link to behavior study] neurogenesis is increased by extensive hippocampal dependent learning (i. e. trace but not delay conditioning, leuner et al. Increase hippocampal capacity and protect old memories from interference (nottebohm 2002, Becker 2005: clear out old memories and facilitate consolidation (kempermann 2002, fenget et al.