BIO SCI 93 Lecture Notes - Lecture 16: Aminoacyl Trna Synthetase, Stop Codon, Polysome
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BIO SCI 93 Full Course Notes
Verified Note
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Document Summary
Genes produce proteins via transcription and then translation. Translation = formation of a protein sequence based off mrna (in ribosomes) Proteins produced targeted to specific cellular location. Trna has specific amino acid on one end and anticodon that complements the mrna codon at the other. Flexible pairing at the 3rd codon base (wobble) allows trna to bind to more than. Correct match b/w trna and amino acid (bounded by aminoacyl- trna synthetase) Correct match b/w trna anticodon and mrna codon. Large ribosomal subunit attaches to the other parts trna enter and attaches to a site. Amino acids are transferred from trna in p site to the trna in a site. Both trnas shift left and the trna in e site exits and another trna comes into open a site. Energy used each time!! (gtp gdp + pi) Multiple ribosomes work simultaneously forming a polyribosome (long chain of ribosomes) to speed up process.