BIO SCI N166 Lecture 6: 6
21 Dec 2016
School
Department
Course
Professor
Document Summary
12-step programs and abstinence-based programs rarely work because they send the addicts back to the environments which contains a lot of cues. Craving: after repeated drug admin. , there is strong desire to attain drug. Tolerance: decreased drug effect after repeated administrations --> over time, need more and more of drug to get same response --> over time, need more and more of drug to get same response. Anticipatory, conditioned response helps to maintain a steady. If we didn"t salivate/didn"t anticipate food, we would have dry mouth. The anticipatory, compensatory response helps to maintain a steady state. Environmental cues help us anticipate --> evoke conditional response. Conditional response does not need to be the same as the unconditional response. Morphine admin (1st time): feels good, blocks pain, feels cold, decreased b. p. , warm skim, dry mouth. Methadone (weak opiod) --> no high, just makes you feel okay. Alcohol and opiates quite gaba neurons that normall inhibit da neurons.
