PSYCH 160A Lecture Notes - Lecture 4: Medical Optical Imaging, Local Field, Pipette
25 Jan 2020
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Document Summary
Measure the electrical activity of the brain. Measures something that correlates with neuronal firing. The recording of pre- & postsynaptic activity through an electrode inserted into the brain. With one electrode (single-unit) or many (multi-unit) Inside the cell (patch-clamping) or outside (extracellular) Most typically are done for single electrodes, extracellular. Intracellular recordings can be achieved but are very difficult. Measuring electrical activity in the extracellular space adjacent to neurons. In the resting state, the inside of the neuron is more negative than the outside. Changes in that ion imbalance can happen in relatively small amounts. Or shift the ion balance dramatically and quickly. The output, or decision of that neuron. Unit recordings in animal studies more often measure the rate of action potentials. The action potential travels in one direction. Start at the axon hillock (base of the cell body), down the axon away from the cell body.
