GE CLST 80A Lecture Notes - Lecture 16: Safe Sex, Menopause, Thymus

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Each individual t-cell and b-cell has a unique receptor on its cell surface that can. Their antigen receptors have 2 binding sites, which make them extremely sticky can. Becomes activated and starts to divide (clonal expansion) Secretes antibodies into the blood to neutralize the specific antigen. After the antigen is eliminated, memory b-cells persist. It is (cid:271)(cid:455) random (cid:272)ha(cid:374)(cid:272)e that a (cid:272)ell"s re(cid:272)eptor atta(cid:272)hes to a (cid:272)orrespo(cid:374)di(cid:374)g a(cid:374)tige(cid:374) How does the adaptive immune system generate specificity? recognize a specific foreign substance (antigen). bind strongly to foreign antigens. If an antigen (like a virus) has already infected a cell, then t-cell becomes activiated. T-cells recognize peptides of the virus that are on the surface of the infected cell, which kill the infected cell. The number of t cells that can recognize a specific antigen is very small, and it goes through clonal expansion to create more t-cells. 24% of them are over 50 years of age.

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