DIET 4475 Lecture Notes - Lecture 52: Iron-Deficiency Anemia, Hypochromic Anemia, Ferritin
Document Summary
Iron stores diminish: routine test of plasma (serum) ferritin, 2nd stage: Iron stores low & transport decreases: plasma ferritin diminishes, circulating iron begins to decrease. Free protoporphyrin rises: final stages, anemia occurs, hemoglobin & hematocrit typically altered, blood cells indicators, mcv (size, mch (avg hgb content, mchc (amt of hgb g/dl, hypochromic, microcytic. Iron deficiency progressed to iron deficiency anemia: hemoglobin cannot be produced, rbcs are small (microcyctic) and pale (hypochromic) and cannot deliver enough oxygen to cells, most common nutritional deficiency, typically premenopausal women, children, athletes. Symptoms of iron deficiency: fatigue, weakness, decreased work capacity, cannot maintain body temp, changes in behavior, prone to infection, adverse pregnancy outcomes. Supplementation: nonheme iron, take with vitamin c or with heme iron, do not take with calcium, ferrous absorbed better than ferric, supplements may interfere with copper and zinc. Answer protects the body against free iron release. Answer a liver-derived hormone that helps regulate iron absorption and transport.
